Should I set my makeup with a setting spray or powder?

You should set your entire face with a translucent powder, my favorite is from Make Up For Ever, but it's a bit pricey. I believe Revlon makes a decent one if you're on the drugstore path. Then, mist the setting spray all over your face, about 3 or so sprays. I personally LOVE Fix+, not only does it set your makeup, but it's also very refreshing. I use it throughout the day; I call it the "caffeine for my face". :)